Q. During translation initiation in prokaryotes, a GTP molecule is needed in
A) formation of formyl-met-tRNA
B) binding of 30S subunit of ribosome with mRNA
C) association of 30S mRNA with formyl-mettRNA
D) association of 50S subunit of ribosome with initiation complex.
Explanation
The initiation of polypeptide chain in prokaryotes is always brought about by the amino acid methionine but it has to be formylated to form tRNA f met. Then methionine binds with tRNA fmet to form f-met-tRNA fmet. This fmet-tRNA fmet complex binds with the mRNA-30S subunit complex using initiation factors IF-2 and IF-1 and GTP.
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.