Q. The association of histone H1 with a nucleosome indicates that

A) DNA replication is occurring
B) the DNA is condensed into a chromatin fibre
C) the DNA double helix is exposed
D) transcription is occurring.
Explanation

Histones help in packaging of DNA. In eukaryotes, DNA packaging is carried out with the help of positively charged basic proteins called histones. Histones are of five types [image:6_image57.wmf], [image:6_image58.wmf]and [image:6_image59.wmf]. The association of [image:6_image60.wmf] histone with nucleosome indicates that DNA remains in its condensed form. Nucleosome is the unit of compaction. [image:6_image61.wmf] is attached over the linker DNA. The linker DNA, consisting of [image:6_image61.wmf]histone connects two adjacent nucleosomes. They together consititute chromatosome. It gives rise to a chromatin fibre after further condensation.

Dr. Abubacker
Reviewed by Dr. Abubacker

Physics Educator & NEET/JEE Specialist

Ph.D. in Physics with 19+ years of teaching experience.