Explanation

Special sequence in the DNA recognized by restriction endonuclease is called palindromic nucleotide sequence. Restriction endonuclease recognizes palindromic sequences in DNA and cuts them The palindromes in DNA are base pair sequences that are the same when read forward (left to right) or backward (right to left) from a central axis of symmetry For example (i) 5’ – G A A T T C – 3’ 3’ – C T T A A G – 5’ (ii) 5’ – G G A T C C -3’ 3’ – C C T A G G -5’