Q. Two enzymes responsible for restricting the growth of bacteriophages in $E.coli$ were isolated. One was methylase and other was restriction endonuclease. What is the significance of methylase?
A) Protection of host DNA from the action of restriction endonuclease by adding methyl group to one or two bases usually with in the sequence recognized by restriction enzyme
B) Able to ligate the two cohesive ends of DNA molecule
C) Able to remove the methyl group and hence, prevent the action of restriction endonuclease on host DNA
D) Able to cut the DNA of bacteriophage at specific sites
Explanation
Protection of host DNA from the action of restriction endonuclease by adding methyl group to one or two bases usually with in the sequence recognized by restriction enzyme
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.