Q. C-peptide of human insulin is
A) A part of mature insulin molecule
B) Responsible for the formation of disulphide bridges
C) Removed during the maturation of pro-insulin to insulin
D) Responsible for its biological activity
Explanation
Removed during the maturation of proinsulin to insulin. Insulin contains two short polypeptide chains, chain A and B-chain linked by disulphide bridge. In mammals, insulin is synthesised as prohormone (that needs to be processed to become mature and functional hormone). It contains an extra stretch called-peptide. C-peptide is absent in mature insulin and is removed during the maturation into insulin
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.