In 1983, Eli Lilly an American company, first prepared two DNA sequences corresponding to A and B-chains of the human insulin and introduced them in the plasmids of $Escherchia\ coli$ to produce insulin chains. Chains A and B were prepared separately, extracted and combined by creating

Question

Dr. Abubacker · Accepted Answer

Production of insulin by recombinant DNA techniques was achieved by an American company, Eli Lilly, in 1983. They prepared two DNA sequences corresponding to A and B-chains of the human insulin and introduction them into the plasmids of E. coli for production. The A and B chains produced were separated, extracted and combined by creating disulphide bonds to form human insulin

Q. In 1983, Eli Lilly an American company, first prepared two DNA sequences corresponding to A and B-chains of the human insulin and introduced them in the plasmids of $Escherchia\ coli$ to produce insulin chains. Chains A and B were prepared separately, extracted and combined by creating

Explanation

Reviewed by Dr. Abubacker

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