Explanation

Colchicine is a poisonous chemical, isolated from seeds and bulbs of autumn crocus (݋ܥ݈ܿℎ݅ܿݑ݉ ܽݑݐݑ݈݉݊ܽ݁(. It blocks spindle formation and thus, inhibits the movement of sister chromatids to the opposite poles. The resulting restitution nucleus includes all the chromatids. As a result, the chromosome number of the cell is doubled, which leads to polyploidy.