Q. Down’s syndrome and Turner’s syndrome occur in human beings due to

A) Monosomic and nullisomic conditions respectively
B) Monosomic and trisomic conditions respectively
C) Trisomic and monosomic conditions respectively
D) Trisomic and tetrasomic conditions respectively
Explanation

In trisomic condition, diploid organism have extra chromosome represented by the chromosomal formula2n + 1 . One of the pairs of chromosomes has an extra member, so that a trivalent may be formed during meiotic prophase, e.g., Down’s syndrome (45+XX or 45+XY), Klinefelter’s syndrome (44 + XXY). In monosomic, diploid organism has one chromosome of a single pair missing with genomic formula 2n − 1. Monosomics can from two kind of gametes, (n) and (n-1), e.g., Turner’s syndrome (44 + X).

Dr. Abubacker
Reviewed by Dr. Abubacker

Physics Educator & NEET/JEE Specialist

Ph.D. in Physics with 19+ years of teaching experience.