Q. Type of substitution takes place in sickle-cell anaemia is
A) Acidic amino acid to an neutral amino acid
B) Glutamic acid by valine
C) GUG to GAG
D) All of the above
Explanation
In sickle-cell anaemia acidic amino acid (glutamic acid) is replaced by neutral amino acid (valine). It is caused because GUG (codes for glutamic acid) or placed by GAG (codes for valine)
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.