In ABO blood group system, inheritance of grouping is controlled by a single autosomal gene on chromosomal-9 with three major alleles A, B, an O ൫I , I and I ൯. The ABO blood group system has at least 6 alleles. On the basis of presence or absence of antigens and antibodies four blood groups (phenotypes) have been differentiated-A, B, AB and O blood groups. The phenotype, genotype, antigen and antibody of blood group ABO. Phen otype Genotyp e Antige n Antibo dy A I ୟ I ୭ , I ୟ I ୟ A b B I ୠ I ୭ , I ୠ I ୠ B a AB I ୟ I ୠ A, B None O I ୭ I ୭ None a, b