Bacilli Calmette Guerin (BCG) is the vaccine for tuberculosis. It was first used in 1921. BCG is the only vaccines available today for protection against tuberculosis. It is most effective in protecting children from the disease. BCG contains a live attenuated (weakened) strain of Mycobacterium bravis. This vaccine was developed by Clamette and Guerin at Pasteur Institutes, Paris.