Chromosomal mutation or change is the sudden inheritable change in the hereditary material of an organism. It caused due to the several ways like deletion, duplication, translocation, inversion, etc. [image:5c_image3.png] Main types of Mutation [table] Loss of Chromosome | Process ; Loss of fragment of chromosome Inversion of fragment of chromosome Attachment of segment of one chromosome to another Repetition of a segment in a chromosome | Deletion Inversion Translocation Duplication [/table] [table] Gene Mutation | Process ; Replacement of one base or more nucleotide Removal of one base or more nucleotide Addition of one base or more nucleotide | Substitution Deletion Addition [/table]