Q. Phenylketonuria, Huntington’s disease and sickle cell anaemia are caused respectively due to disorders associated with
A) Chromosome-7, chromosome-11 and chromosome-12
B) Chromosome-11, Chromosome-4 chromosome-12
C) Chromosome-7, chromosome-12 and chromosome-11
D) Chromosome-12, chromosome-4 and chromosome-11
Explanation
Phenylketonuria (PKU) is homozygous recessive autosomal disorder associated with metabolism and the gene for it is present on chromosome-12. Huntington’s disease (Huntington’s chorea) is a dominant autosomal disorder due to an allele on short arm of chromosome-4. Sickle cell anaemia is due to codominant autosomal allele $Hb^{S}$ present on chromosome-11.
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.