Explanation

[table] Disorders | Autosomal/Sex Linked | Symptoms | Effects ; Down’s syndrome | Autosomal aneuploidy (trisomy, +21) | Mongolian eyefold (epicanthus), open mouth, protruded tongue, projected lower lip, many loops on finger tip, palm crease | Retarded mental development IQ (below 40) ; Turner’s syndrome | Sex chromosomal monosomy 44 + XO | Short stature females (<5’), webbed neck, body hair absent menstrual cycle absent. Sparse pubic hair, underdeveloped breasts narrow lips puffy fingers | Sterile hearing problem ; Klinefelter’s syndrome | Sex chromosomal aneuploidy (tri/tetrasomy of X chromosome) 44+XXY 44+XXXY | The males are tall with long legs, testes small, sparse body hair, Barr body present, breast enlargement | Gynaecomastia azospermia sterile [/table]