Q.
List the following alkoxide nucleophile in decreasing order of their $S_{N}\$2 reactivity
1. $Me_{3}CO^{-}$ 2.$MaO^{-}$ 3.$MeCH_{2}O^{-}$ 4. ${Me}_{2}CHO^{-}$ 5.
A) 2>3>5>4>1
B) 5>3>2>1>4
C) 1>5>2>3>4
D) 3>5>1>2>3
Explanation
(a)
Epoxide is ambident substrate for nucleophilic substitution reactions. In protonated epoxide carbon-2 and carbon-3 both aquire some positive charge due to the highly electronegative atom
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Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.