Q. Which of the following would undergo Hofmann reaction to give a primary amine?
A) $RCOCl$
B) $RCONHCH_{3}$
C) $RCONH_{2}$
D) $RCOOR'$
Explanation
(c)
Hofmann reaction In this reaction acid amide group reacts with $Br_{2}$ in presence of NaOH or KOH to give primary amine group. The amine is one carbon less than the parent amide. So, the reaction is known as Hofmann degradation reaction.
$RCONH_{2} + Br_{2} + 4KOH\overset{\ \ \ \ \ \ \mathrm{\Delta}\ \ \ \ }{\rightarrow}RNH_{2} + 2KBr + K_{2}CO_{3} + 2H_{2}O$
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.