Q. Statements related to human Insulin are given below. Which statement(s) is/are correct about genetically engineered Insulin? A. Pro-hormone insulin contain extra stretch of C-peptide B. A-peptide and B-peptide chains of insulin were produced separately in $E.\ coli$, extracted and combined by creating disulphide bond between them. C. Insulin used for treating Diabetes was extracted from Cattles and Pigs. D. Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone. E. Some patients develop allergic reactions to the foreign insulin. Choose the most appropriate answer from the options given below.
A) C, D and E only
B) A, B and D only
C) B only
D) D and E only
Explanation
[Solution] In genetically engineered insulin (Eli Lilly), the A and B chains were produced separately in $E.\ coli$ and joined by disulphide bonds; the other statements relate to natural/animal insulin. Per the source key, B only. Answer (3).
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.