[Solution from source] Plasmodium multiplies asexually inside RBCs and then bursts them, releasing new merozoites to infect fresh RBCs along with the toxin haemozoin. This bursting happens in cycles (every 48 hours in vivax), which is when the chill and high fever recur. Sporozoites enter through the mosquito bite and go to the liver, not RBCs. Answer (3).