Q. Krebs’ cycle was discovered by Krebs in pigeon muscles in 1940. Which step is called gateway step/link reaction/transition reaction in respiration?

A) Glycolysis
B) Formation of acetyl Co-A
C) Citric acid formation
D) ETS terminal oxidation
Explanation

If oxygen is not available, pyruvic acid undergoes anaerobic respiration/fermentation, but under aerobic condition, the pyruvic acid enters into mitochondria and converted to Acetyl Co-A. Acetyl Co-A functions as substrate entrant for Krebs’ cycle so, a connecting link between glycolysis and Krebs’ cycle. Glycolysis is the process of breakdown of glucose (hexose sugar) to two molecules of pyruvic acid through a series of enzyme mediated reactions. It occurs in cytoplasm and is common both to aerobic and anaerobic respiration. Last product is pyruvic acid.

Dr. Abubacker
Reviewed by Dr. Abubacker

Physics Educator & NEET/JEE Specialist

Ph.D. in Physics with 19+ years of teaching experience.