[Solution from source] Bacillus thuringiensis makes Bt toxin as an inactive protoxin crystal; the alkaline pH of the insect gut solubilises and activates it, and it binds the midgut epithelium, creating pores that kill the insect. It is not active inside the bacterium, which is why the bacterium is unharmed, and it does not act on the ovaries. Answer (4).