Identify $A$ and $B$ in the given reaction Pyruvic acid +Co-A $+ NAD^{+}\underset{Pyruvate\ dehydrogenase}{\overset{\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ Mg^{2 +}\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ }{\rightarrow}}A + B + NADH + H^{+}$

Question

Dr. Abubacker · Accepted Answer

Pyruvic acid is 3C-compound. One of the three carbon atoms of pyruvic acid is oxidised to carbon dioxide in a reaction called oxidative decarboxylation. Pyruvate is first decarboxylated and then oxidised by the enzyme pyruvate dehydrogenase. The combination of the remaining 2-carbon acetate unit is readily accepted by a sulphur containing compound, coenzyme A (Co-A) to form acetyl Co-A

Q. Identify $A$ and $B$ in the given reaction Pyruvic acid +Co-A $+ NAD^{+}\underset{Pyruvate\ dehydrogenase}{\overset{\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ Mg^{2 +}\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ }{\rightarrow}}A + B + NADH + H^{+}$

Explanation

Reviewed by Dr. Abubacker

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