Q. The Okazaki fragments in DNA chain growth

A) polymerize in the 3'-to-5' direction and form replication fork
B) prove semi-conservative nature of DNA replication
C) polymerize in the 5'-to-3' direction and explain 3'-to-5' DNA replication
D) result in transcription
Explanation

[Solution from source] DNA polymerase can add nucleotides only in the 5'->3' direction, so on the lagging strand short Okazaki fragments are made 5'->3' and later joined by DNA ligase. This explains how that strand is built overall in the 3'->5' direction. No polymerase works 3'->5', and semi-conservative replication was proved by Meselson and Stahl, not by Okazaki fragments. Answer (3).

Dr. Abubacker
Reviewed by Dr. Abubacker

Physics Educator & NEET/JEE Specialist

Ph.D. in Physics with 19+ years of teaching experience.

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