Q. During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
A) AATT
B) CACC
C) TATA
D) TTAA
Explanation
[Solution from source] RNA polymerase is positioned at the promoter by the TATA box (Pribnow box in prokaryotes), an AT-rich consensus sequence TATAAT/TATAAAA about 10-30 bases upstream of the start site. AATT and TTAA are not the recognised promoter consensus. Answer (3).
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.