Q. An example of non-competitive inhibition is

A) The inhibition of succinic Dehydrogenase by Malonate
B) Cyanide action on cytochrome oxidase
C) Sulpha drug on folic acid synthesizing bacteria
D) The inhibition of Hexokinase by glucose 6-phosphate
Explanation

In the non-competitive inhibition of enzymes, the inhibitor (cyanide) has no structural similarity with the substrate (cytochrome-c) and binds to the enzyme at a point other than its active site which leads to change in globular structure of enzyme. Hence, even if the substrate is able to bind with the enzyme, catalysis will not take place.

Dr. Abubacker
Reviewed by Dr. Abubacker

Physics Educator & NEET/JEE Specialist

Ph.D. in Physics with 19+ years of teaching experience.