Enterokinase or enteropeptidase is secreted by crypts of Leibrekuhn in the duodenum. It is a serine protease enzyme. When food enters into the duodenum, enterokinase converts proenzyme trypsinogen into trypsin, which indirectly activating a number of pancreatic digestive enzyme. It also activates other proteases in the pancreatic juice. Thus, absence of enterokinase affects the conversion of proteases intosmall peptides.