Liver, the largest digestive gland of the body performs various function. The synthesis of glucose or glycogen from non-carbohydrate sources such as amino acids, glycerol, etc, is called gluconeogenesis. The process takes place when glycogen supply in the liver is exhausted. Gluconeogenesis involves the conversion of excess of glucose into glycogen by liver with the help insulin hormone. Glycogenolysis involves the conversion of glycogen into glucose