$\rho CO_{2}$ is low and $\rho O_{2}$ is high in alveoli. When $\rho CO_{2}$ is high and $\rho O_{2}$ is low as in the tissues, more binding of $CO_{2}$ occurs whereas when the $\rho CO_{2}$ is low and $\rho O_{2}$ is high as in the alveoli, dissociation of $CO_{2}$ from carbamino haemoglobin takes place, i.e., $CO_{2}$ which is bound to haemoglobin from the tissues is delivered to alveoli