Q. What happens in Hamburger shift?
A) $HCO_{3}^{-}$ ions move out from plasma and $Cl^{-}$ ions enters into RBC
B) $CO_{3}^{-}$ ions move out from plasma and $Cl^{-}$ ions enters into RBC
C) $H^{+}$ ions move out from plasma and $Cl^{-}$ ions enters into RBC
D) ${HCO}_{3}$ ions move out from plasma and $H^{+}$ ions enters into RBC
Explanation
$CO_{2} + H_{2}O\overset{\ \ Carbonic\ Anhydrase\ \ }{\rightarrow}\ H_{2}CO_{3} \rightleftharpoons HCO_{3}^{-} + H^{+}$ To maintain the neutrality of the plasma, $HCO_{3}^{-}$ ions diffuses out into the plasma and ions enter into the RBC. The chloride content of the RBCs increases when oxygenated blood becomes deoxygenated This is known as Hamburger shift or chloride shift. Because of it, the $Cl^{-}$ content of the red cells in the venous blood is significantly greater than in arterial blood
Reviewed by Dr. Abubacker
Physics Educator & NEET/JEE Specialist
Ph.D. in Physics with 19+ years of teaching experience.