Explanation

Juxtaglomerular apparatus (JGA) operates a multihormonal Renin-Angiotensin-Aldosterone System RAAS. JGA releases an enzyme renin in the blood, which initiates chemical reactions that produces angiotensin-II, a potential stimulator of aldosterone (mineralocorticoids) release by the glomerulosa cell. It increases blood pressure, blood volume and completes the feedback circuit by supporting the release of renin.