Diabetes mellitus (due to hyposecretion of insulin) It is characterised by (i) Hyperglycemia High level of blood glucose (300 to 200 mg/100 mL) (ii) Polyuria Excessive urination (iii) Polydipsia Excessive thirst (iv) Glycosuria Glucose in urine (v) Polyphagia Excessive eating (vi) Increased oxidation of fat (vii) Loss of body weight and tiredness (vii) Dehydration